Monday, March 21, 2011

Black Elderberries Knock Out Flu Viruses

Black elderberry extract has been found to ward off influenza A and B viruses and bacteria associated with upper respiratory infections, according to a new study published online at BMC Complementary and Alternative Medicine.

Researchers at Justus-Liebig University analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus.

The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid cultures using the extract at concentrations of 5%, 10%, 15% and 20%. The inhibitory effects were determined by plating the bacteria on agar plates. The inhibitory potential of the extract on the propagation of human pathogenic H5N1-type influenza A virus isolated from a patient and an influenza B virus strain also was investigated using MTT and focus assays.

The researchers found a standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. The liquid extract also displays an inhibitory effect on the propagation of human pathogenic influenza viruses.

The findings suggest Rubini elderberry liquid extract is active against human pathogenic bacteria as well as influenza viruses.

Sources:

* BMC Complementary and Alternative Medicine: Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

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