Drinking a glass of polyphenol-rich Concord grape juice may help
boost neurocognitive function in older adults with mild memory decline,
according to a new study published in the Journal of Agricultural and Food
Chemistry.
Polyphenol compounds found in berry fruits, in particular
flavonoids, have been associated with health benefits including improvement in
cognition and neuronal function with aging. Concord grape juice contains
polyphenols, including anthocyanins and flavanols, and previous research has
shown improvement in a number of human health conditions with grape juice
supplementation.
For the study, researchers at the University of Cincinnati
Academic Health Center enrolled older adult subjects (average age 77) with mild
cognitive impairment in a randomized, double-blind, placebo-controlled study.
Participants consumed Concord grape juice or placebo daily for 16 weeks and
were administered assessments of memory function and brain activation pre- and
post-intervention.
Participants who consumed grape juice showed reduced semantic
interference on memory tasks. Relatively greater activation in anterior and
posterior regions of the right hemisphere was also observed with functional
magnetic resonance imaging in the grape juice treated subjects. These findings
provide further evidence that Concord grape juice can enhance neurocognitive
function in older adults with mild memory decline.
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